EFFECT: pharmaceutics.
SUBSTANCE: invention relates to a method for producing compounds of class 3-aroyl-N-benzyl-2-hydroxy-1-oxobenzo[d]pyrrolo[2,1-b]thiazole-3a(1H)-carboxamides with antioxidant activity, which can also be used as starting products for the synthesis of new heterocyclic systems and drugs in pharmacology. The method consists in the interaction of 3-aroylpyrrolo[2,1-c][1,4]benzothiazine-1,2,4-triones with benzylamine in anhydrous toluene medium, with further processing of the reaction mass and isolation of the target products.
EFFECT: development of a simple method for the synthesis of 3-aryl-N-benzyl-2-hydroxy-1-oxobenzo[d]pyrrolo[2,1-b]thiazole-3a(1H)-carboxamides.
I, III: Ar=C6H5 (а); Ar=C6H4Me-4 (б); Ar=C6H4Cl-4 (в).
1 cl, 1 tbl, 4 ex
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