METHOD FOR SELECTING SHORTENED CHEMOTHERAPY REGIMENS IN THE TREATMENT OF RESPIRATORY TUBERCULOSIS IN CHILDREN FROM FOCI WITH MULTIDRUG RESISTANCE OF THE PATHOGEN Russian patent published in 2022 - IPC G01N33/48 A61K31/536 A61P31/06 

Abstract RU 2784464 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to phthisiology, and can be used in the formation of chemotherapy regimens for respiratory tuberculosis in children. In cases of a limited tuberculous process in a child without bacterioexcretion, the absence of concomitant pathology in a child, an established contact with a patient with tuberculosis with a multidrug-resistant pathogen and preserved sensitivity to drugs of the fluoroquinolone group, a four-component starting combination of drugs is performed. The duration of the intensive phase is at least 3 months and the duration of the use of drugs from the fluoroquinolone group is at least 6 months. After that, three-component therapy is started in the continuation phase of treatment with a total chemotherapy period of 9 months. In cases of using a four-component combination for less than 3 months or fluoroquinolones for less than 6 months, the total course of chemotherapy is extended to 12 months.

EFFECT: method provides an increase in the effectiveness of treatment of tuberculosis of the respiratory system in children, a decrease in the possibility of adverse reactions.

1 cl, 1 dwg, 1 tbl, 3 ex

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RU 2 784 464 C1

Authors

Gubkina Marina Fedorovna

Petrakova Irina Yurevna

Khokhlova Yuliya Yurevna

Sterlikova Svetlana Sergeevna

Yukhimenko Natalya Valentinovna

Dates

2022-11-25Published

2022-02-22Filed