FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to phthisiology, and can be used in the formation of chemotherapy regimens for respiratory tuberculosis in children. In cases of a limited tuberculous process in a child without bacterioexcretion, the absence of concomitant pathology in a child, an established contact with a patient with tuberculosis with a multidrug-resistant pathogen and preserved sensitivity to drugs of the fluoroquinolone group, a four-component starting combination of drugs is performed. The duration of the intensive phase is at least 3 months and the duration of the use of drugs from the fluoroquinolone group is at least 6 months. After that, three-component therapy is started in the continuation phase of treatment with a total chemotherapy period of 9 months. In cases of using a four-component combination for less than 3 months or fluoroquinolones for less than 6 months, the total course of chemotherapy is extended to 12 months.
EFFECT: method provides an increase in the effectiveness of treatment of tuberculosis of the respiratory system in children, a decrease in the possibility of adverse reactions.
1 cl, 1 dwg, 1 tbl, 3 ex
Authors
Dates
2022-11-25—Published
2022-02-22—Filed