FIELD: biotechnology.
SUBSTANCE: plasmid structure px330+P2rx3-sg1 for producing transgenic mice homozygous for the null allele of the P2rx3 gene. A line of mice homozygous for the null allele of the P2rx3 gene, as well as a method for its production, are also disclosed.
EFFECT: invention is effective for testing substances for the role of a P2X3 blocker.
6 cl, 5 dwg, 3 ex
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